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CASE REPORT
Year : 2019  |  Volume : 7  |  Issue : 1  |  Page : 50-52

Orbital Rosai–Dorfman disease: A case report and literature review


1 Department of Emergency Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
2 Department of Lid, Lacrimal, Orbit and Oncology, Maghrabi Eye and Ear Hospital, Jeddah, Saudi Arabia
3 Department of Ophthalmology, King Abdullah Medical City, Makkah, Saudi Arabia
4 Department of Pathology, King Faisal Specialist Hospital and Research Centre; Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

Correspondence Address:
Dr. Jaudah Al-Maghrabi
Department of Pathology, Faculty of Medicine, King Abdulaziz University, PO Box 80205, Jeddah 21589
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JMAU.JMAU_45_18

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A 53-year-old male presented with dropping of the right eyelid associated with decreased visual acuity for 4 months. He also complained of vertical diplopia especially when looking down. Ophthalmological examination revealed right blepharospasm associated with right hypertropia. There was palpable mass at the inferomedial aspect of the right eye. Magnetic resonance imaging revealed abnormal signal intensity in the right orbit inferior aspect occupying the orbital floor and measured 2.7 cm × 2.5 cm × 1.2 cm and showed enhancement on the postcontrast study. The patient underwent complete excision of the tumor. Histological examination of the mass revealed histiocytic proliferation with emperipolesis, with positive S100, positive CD68, and negative CD1a staining. These histological and immunohistochemical features are consistent with extranodal Rosai–Dorfman disease. There was no complication or recurrence after the complete excision.


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