Figure 3: Histopathological photomicrographs of kidney of Heteropneustes fossilis under control conditions (Co), glyphosate-treated laboratory conditions (GL), and glyphosate-treated field conditions (GF). (A) Normal proximal convoluted tubule (PCT), distal convoluted tubule (DCT), Bowman's capsule and glomerulus (G) under light microscopy (C, 1000×). (B) Degeneration of PCT and DCT (arrow), vacuolation in hematopoietic tissues (broken arrow) and loss of hematopoietic tissue (square) under light microscopy (GL, 1000×). (C) Light microscopy showing normal structure of PCT and DCT and vacuolation (broken arrow; GF, 400×). (D) Normal appearance of kidney with electron-dense mitochondria (M) and nucleus (N) under TEM (Co, 4000×). (E) Dilation and fragmentation of rough endoplasmic reticulum (square), degeneration in mitochondria (bold arrow) and severe vacuolation (broken arrow) underTEM (GL, 5000 ×). (F) Normal appearance of kidney under TEM (GF, 6300×). TEM = transmission electron microscopy.