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  Indian J Med Microbiol
 

Figure 2: Electron micrographs of ultrathin sections of rat sciatic nerve of the (A, B) Control Group showing, normal myelinated (mn) and unmyelinated (un) nerve fibers, and axoplasm (Ax) of myelinated fibers containing multiple microtubules and mitochondria (M), that are wrapped in a thick myelin sheath with compact lamellar structure and surrounded by Schwann cells (Sch). (C–H) Aspartame Group showing blood vessels (arrow) lined by endothelial cells and containing (C, D) monocytes with irregular nuclei (curved arrow), (E) focal lysis (biffed arrow) of myelin sheath with (E, F) appearance of redundant myelin (double arrow) and (G, H) formation of myelin loop (arrow head).

Figure 2: Electron micrographs of ultrathin sections of rat sciatic nerve of the (A, B) Control Group showing, normal myelinated (mn) and unmyelinated (un) nerve fibers, and axoplasm (Ax) of myelinated fibers containing multiple microtubules and mitochondria (M), that are wrapped in a thick myelin sheath with compact lamellar structure and surrounded by Schwann cells (Sch). (C–H) Aspartame Group showing blood vessels (arrow) lined by endothelial cells and containing (C, D) monocytes with irregular nuclei (curved arrow), (E) focal lysis (biffed arrow) of myelin sheath with (E, F) appearance of redundant myelin (double arrow) and (G, H) formation of myelin loop (arrow head).